Fibromyalgia

Revealing the new drugs that actually work for treating the fibromyalgia features!

New fibro drugs

While living with fibromyalgia, various medications followed with alternative therapies can improve the overall quality of life.

Disturbed sleep, diffused pain, fatigue, depression and anxiety, and irritable bowel syndrome are the common symptoms of fibromyalgia.

Every person with fibromyalgia can experience different symptoms. So, fibro symptoms differ from person to another.

Due to the varying symptoms, fibromyalgia is often misdiagnosed. With the help of tender point’s presence, your doctor can make the definitive diagnose of fibromyalgia, otherwise, there is no such lab test or scans available to confirm the disease.

Since fibromyalgia is a chronic disease and can persist throughout your life, the selection of the management approach is vital for your overall health.

Presently, new researches and studies have been conducting to formulate the absolute cure for fibromyalgia, but only the medications treating the fibro features work best to provide the eventual pain and discomfort relief.

Do you know what those drugs are? Well, before revealing about them, you should know that which medications are included in the fibromyalgia treatment plan and how they can treat the symptoms.

Fibromyalgia treatment- the combination of pharmacological and non-pharmacological approaches

Of course, pharmacological and non-pharmacological approaches, both work best for managing the symptoms of fibromyalgia.

As the cure of symptoms is available, your doctor can prescribe you the medication that can ease the most-disturbing-symptom.

Initially, the antidepressant is the first medicine that usually doctors prescribe to relieve the pain and fatigue. Also, sleep problems and depression could be improved with the help of the antidepressants.

Painkillers are also prescribed according to the severity and intensity of pain. Anticonvulsants and muscle relaxants are also used to reduce pain, fatigue and muscle stiffness.

Non-pharmacological approaches can help to soothe off your nerves by sending positive signals to your brain and releasing the happy hormones in your body.

Try yoga, tai chi, massage, acupuncture, meditation, and deep breathing to get the optimal relief from fibro symptoms.

What new drugs are effective for treating fibromyalgia?

Undoubtedly, the formulation of new drugs is the breakthrough for treating the symptoms of fibromyalgia.

However, some drugs are still on-hold from FDA and prescribing as an off-label drug.

1- IMC-1

This drug is the combination of two drugs, namely, famciclovir (Famvir) and celecoxib (Celebrex).

Dr. William Pridgen, the discoverer of this combo, believed that HSV1 virus (commonly cause cold cores) can be one of the reasons of fibromyalgia.

While treating the gut issues in fibromyalgia patients, he created this theory based on his clinical practice and results in Tuscaloosa, Ablama.

Pridgen observed that fibro symptoms increases and decreases due to the activation of undetected virus in your body.

To test his theory, he prescribed that antiviral drug to his patient. As a result, slight improvement has been observed in the patients.

Simultaneously, he prescribed the Celebrex to his patients, expecting that anti-inflammatory will work for reducing overall pain.

Patients who have taken both, antiviral as well as Celebrex reported the significant improvement in the fibromyalgia symptoms.

Pridgen said that the pain reduction levels were as same or comparable with other approved drugs for fibromyalgia.

He further added that pain wasn’t only has reduced in people with fibromyalgia; yet, the overall impact of this drug is impressive.

Pridgen continued that it is definitely different (from other fibromyalgia drugs).

He further said that instead of treating the pain perception, they’ve discovered the root cause of fibromyalgia.

For the millions of people suffering fibromyalgia, IMC-1 is a potentially new option of a drug for treating the excruciating condition.

The study has been conducted in two phases; the third phase will be conducted by next year in which 12,000 patients will be enrolled.

The side effects were lower and it is expected that this drug will be available in the market within three years.

However, several studies are also important to be conducted to confirm the association of HIV1 virus with the fibromyalgia.

2- Sodium Oxybate ( Xyrem)

Sodium oxybate is the form of gamma hydroxybutyrate (GHB) which is an endogenous metabolite of GABA, a main inhibitory neurotransmitter.

Sodium oxybate is commonly used to treat narcolepsy, a condition referred to the excessive daytime sleepiness.

Sodium oxybate is on-hold from the FDA because of its side effects. This drug has the multiple benefits when it comes to the treatment of fibromyalgia treatment.

The GHB release the serotonin, letting your mood improved. Also, it has the effect similar to opioids, providing you the analgesic effects.

The effects of Sodium oxybate on the fibromyalgia patients are satisfactory. In one study, it is concluded that the administration of sodium oxybate shown significant improvement in all the clinical spheres of fibromyalgia.

Along with decreasing fatigue and pain, this drug can improve the sense of overall well-being.

Another study conducted in 2003 stated that sodium oxybate has positive effects for treating fibromyalgia.

It was concluded that morning stiffness, pain, sleep, and fatigue has also been improved with its administration for the controlled time period.

Despite the sodium oxybate has remarkable effects for treating fibromyalgia symptoms; it has been withdrawn from FDA due to its higher risk of abuse.

Researchers also concluded the theory regarding fibromyalgia and sodium oxybate that the sleep duration was significantly increased in the people with fibromyalgia while taking xyrem.

Hence, the studies have provided evidence that the sodium oxybate is effective in patients with fibromyalgia due to the improvement in pain, fatigue, and sleep.

3- Mirogabalin (lyrica)

This drug has been approved in 2007, but, this was thrilling news among the fibromyalgia population. Do you know why? Well, lyrica is popular due to its troubling side effects.

Though, lyrica can drastically reduce the pain, but it has a risk of causing serious side effects.

New drug named as mirogabalin can relieve pain while binding with the calcium channels of your body.

As compared to other drugs, mirogablin has a long duration of action and unique binding profile.

Mirogablin has fewer side effects and even, it can work better than lyrica. However, millions are investing in order to prove its efficacy.

REFERENCES:

http://wholehealthchicago.com/2009/07/14/two-new-drugs-for-fibromyalgia-that-actually-work/

http://nationalpainreport.com/three-new-fibromyalgia-drugs-could-be-on-the-way-8830514.html

http://www.webmd.com/fibromyalgia/features/treating-fibromyalgia-pain-medication-options

https://www.sciencedaily.com/news/health_medicine/fibromyalgia/

https://www.ncbi.nlm.nih.gov/pubmed/27684492

http://www.webmd.com/fibromyalgia/guide/fibromyalgia-treatment-medications-that-can-and-cant-help?page=2

http://www.news-medical.net/news/20141118/New-oral-medication-shows-promise-in-treating-fibromyalgia.aspx

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382678/

http://www.webmd.com/fibromyalgia/fibromyalgia-pain-10/fibromyalgia-creating-treatment-plan?page=2

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